The story of the Center for Medical Genetics (CMG) at the University Hospital Antwerp (UZA) began in 1964 with a modest consultation service for genetic testing and advice at the former Bunge Institute in Berchem. This service, catering to patients with neuromuscular disorders and/or mental disabilities, was accompanied by a chromosome research laboratory nestled in the scientific wing of the institute.

As the years passed, the CMG grew and evolved. In 1967, a new laboratory was established to diagnose inherited metabolic diseases, expanding the genetic services to a larger group of patients. The need for diverse tissues, such as skin cells, for biochemical investigations led to the creation of a tissue culture laboratory. By 1971, this laboratory had begun examining amniotic fluid cells for prenatal diagnosis, marking a significant milestone in the center's history.

The year 1978 brought change as the Born-Bunge Foundation moved to the campus of the University Institution Antwerp (UIA) in Wilrijk. While most laboratories remained under the foundation's management, the genetic department was integrated into Antwerp University, officially becoming the Center for Medical Genetics. The following year, a consultation service for genetic disorders was established at the UZA in Edegem, further expanding the center's reach.

Innovation continued to drive the CMG forward. In 1985, the center introduced the chorionic villus sampling test, and two years later, a molecular laboratory for DNA testing was launched. These advancements showcased the center's commitment to staying at the forefront of genetic research and diagnostics.

The year 2012 marked a turning point for the CMG with the acquisition of two Illumina Next Generation Sequencing devices. These cutting-edge tools revolutionized both genetic research and diagnostics, propelling the center to new heights.

Today, the CMG stands as a leading genetic center in the province of Antwerp, proudly recognized as one of the eight genetic centers in Belgium. Its journey, spanning over half a century, is a testament to the dedication, innovation, and growth that have shaped its legacy in the field of medical genetics.